新着

PSP

H Geerts, P Roberts and A Spiros (2013) PSP, "A Quantitative System Pharmacology Computer Model for Cognitive Deficits in Schizophrenia" (link) いいなあ、これ。

CPT

R Bruno, F Mercier and L Claret (2013) CPT, "Model-Based Drug Development in Oncology: What’s Next?" (link) なんとなく、必読な感じがする。

CPT

J Hansen and R Iyengar (2013), "Computation as the Mechanistic Bridge Between Precision Medicine and Systems Therapeutics" (link) せっかく購読してるのに Free access だと悔しい^^;

アルツハイマー

Mahesh N. Samtani, Nandini Raghavan, Yingqi Shi, Gerald Novak, Michael Farnum, Victor Lobanov, Tim Schultz, Eric Yang, Allitia DiBernardo, Vaibhav A. Narayan, the Alzheimer' s Disease Neuroimaging Initiative (2012) BJCP, "Disease progressi…

SimCYP と OST

Dumont C, Mentré F, Gaynor C, Brendel K, Gesson C, Chenel M. (2012) Clin Pharmacokinet, "Optimal Sampling Times for a Drug and its Metabolite using SIMCYP Simulations as Prior Information" (link) タイトルから一瞬思うような衝撃は実はない。 …

TDM ソフト

Fuchs, Aline; Csajka, Chantal; Thoma, Yann; Buclin, Thierry; Widmer, Nicolas (2012) Clin. Pharmacokinet, "Benchmarking Therapeutic Drug Monitoring Software: A Review of Available Computer Tools" (link) $49.95 を出すほどでもないな、とあきら…

J PKPD

Choy S, Hénin E, van der Walt JS, Kjellsson MC, Karlsson MO. (2012) "Identification of the primary mechanism of action of an insulin secretagogue from meal test data in healthy volunteers based on an integrated glucose-insulin model" (link)

PSP

H Geerts, A Spiros, P Roberts and R Carr (2012) "Has the Time Come for Predictive Computer Modeling in CNS Drug Discovery and Development?" (link)

Clin Pharmacokinet

Paule, Ines; Girard, Pascal; Freyer, Gilles; Tod, Michel (2012) Clin Pharmacokinet, "Pharmacodynamic Models for Discrete Data" (link)

CPT

L Claret, J-F Lu, R Bruno, C-P Hsu, Y-J Hei and Y-N Sun (2012) CPT, "Simulations Using a Drug–Disease Modeling Framework and Phase II Data Predict Phase III Survival Outcome in First-Line Non–Small-Cell Lung Cancer" (link) 今これに ¥3,300 …

J PK/PD を 2 本

James A. Rogers, Daniel Polhamus, William R. Gillespie, Kaori Ito, Klaus Romero, Ruolun Qiu, Diane Stephenson, Marc R. Gastonguay and Brian Corrigan (2012) J.PKPD, "Combining patient-level and summary-level data for Alzheimer’s disease mod…

EJCP

Tanaka J, Kasai H, Shimizu K, Shimasaki S, Kumagai Y. (2012) EJCP, "Population pharmacokinetics of phenytoin after intravenous administration of fosphenytoin sodium in pediatric patients, adult patients, and healthy volunteers" (link) Free…

AAPS J

Bonate PL, Strougo A, Desai A, Roy M, Yassen A, van der Walt JS, Kaibara A, Tannenbaum S. (2012), "Guidelines for the Quality Control of Population Pharmacokinetic-Pharmacodynamic Analyses: an Industry Perspective" (link) いわゆる「K 氏」

J PKPD

Lagishetty CV, Vajjah P, Duffull SB. (2012) J PKPD, "A reduction in between subject variability is not mandatory for selecting a new covariate" (link) え? Mandatory と考える流派があるのか?

CPT

D R Mould (2012) "Models for Disease Progression: New Approaches and Uses" (link)

J PK/PD

Yuyan Jin, Robert Bies, Marc R. Gastonguay, Norman Stockbridge, Jogarao Gobburu and Rajanikanth Madabushi (2012), "Misclassification and discordance of measured blood pressure from patient’s true blood pressure in current clinical practice…

POSTHOC の SE

Kang D, Bae KS, Houk BE, Savic RM, Karlsson MO. (2012) Korean J Physiol Pharmacol. "Standard Error of Empirical Bayes Estimate in NONMEM® VI" (link) ようやくこの話題が出た。 もっとも注目すべきは、こういう雑誌にこの内容が出た、ということで…

J PKPD

Jun Shen, Alison Boeckmann and Andrew Vick (2012), "Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model)" (link) 吸収のモデル

J PKPD

Maud Delattre, Radojka M. Savic, Raymond Miller, Mats O. Karlsson and Marc Lavielle (2012), "Analysis of exposure–response of CI-945 in patients with epilepsy: application of novel mixed hidden Markov modeling methodology" (link) いいなあ

JCP

Jun Yang, Hong Zhao, Christine Garnett, Atiqur Rahman, Jogarao V. Gobburu, William Pierce, Genevieve Schechter, Jeffery Summers, Patricia Keegan, Brian Booth, Yaning Wang (2012) JCP, "The Combination of Exposure-Response and Case-Control A…

Schizophrenia の M&S

Pilla Reddy V, Kozielska M, Johnson M, Suleiman AA, Vermeulen A, Liu J, de Greef R, Groothuis GM, Danhof M, Proost JH (2012) Clin Pharmacokinet, "Modelling and Simulation of the Positive and Negative Syndrome Scale (PANSS) Time Course and …

Moxifloxacin と QT

Philippe Grosjean and Saïk Urien (2012) J. PKPD, "Moxifloxacin versus placebo modeling of the QT interval" (link)

J PKPD

B. D. Lacroix, L. E. Friberg and M. O. Karlsson (2012), "Evaluation of IPPSE, an alternative method for sequential population PKPD analysis" (link)

CPT

D E Salazar, S H Song, J Shi, S Rohatagi, R Heyrman, D R Wada and T J Carrothers (2012) "The Use of Modeling and Simulation to Guide Clinical Development of Olmesartan Medoxomil in Pediatric Subjects" (link)

J PKPD

Leonid Gibiansky, Ekaterina Gibiansky and Robert Bauer (2012), "Comparison of Nonmem 7.2 estimation methods and parallel processing efficiency on a target-mediated drug disposition model" (link)

JCP

Honghui Zhou, Yuko Tsukamoto, and Hugh M. Davis (2011, Online First) "Should Clinical Pharmacokinetic Bridging Studies Between Caucasian and Asian Populations Be Required for Approval of Monoclonal Antibodies?" (link) あ、T さん。

CPT

J W Mandema, M Gibbs, R A Boyd, D R Wada and M Pfister (2011) CPT, "Model-Based Meta-Analysis for Comparative Efficacy and Safety: Application in Drug Development and Beyond" (link)

BJCP

David Ternant, Guillaume Cartron, Emilie Hénin, Michel Tod, Pascal Girard, Gilles Paintaud (2011) BJCP, "Model-based design of rituximab dosage optimisation in follicular non-Hodgkin's lymphoma" (link)

日本の事例

Mayumi Hasegawa, Yasuhiko Imai, Masaki Hiraoka, Kiyomi Ito and Amit Roy (2011) J.PKPD, "Model-based determination of abatacept exposure in support of the recommended dose for Japanese rheumatoid arthritis patients" (link) The exposure–resp…

BJCP

Denis Garot, Renaud Respaud, Philippe Lanotte, Nicolas Simon, Emmanuelle Mercier, Stephan Ehrmann, Dominique Perrotin, Pierre-François Dequin, Chantal Le Guellec (2011) BJCP, "Population pharmacokinetics of ceftriaxone in critically ill se…