Martin Bergstrand, Erik Söderlind, Ulf G Eriksson, Werner Weitschies and Mats O Karlsson (2011) "A Semi-mechanistic Modeling Strategy to Link In Vitro and In Vivo Drug Release for Modified Release Formulations"

これを見逃していた。 Maria C. Kjellsson, Daniele Ouellet, Brian Corrigan and Mats O. Karlsson (2011) "Modeling Sleep Data for a New Drug in Development using Markov Mixed-Effects Models" Tarundeep Kakkar, Cynthia Sung, Leonid Gibiansky, Th…

Comets, E., Brendel, K., Mentre, F. (2011) JCP, "Why Should Prediction Discrepancies Be Renamed Standardized Visual Predictive Check?" 研究会の関係者必読ですかね。私は未読。未入手。

Hao Zhu and Yaning Wang (2011) J. PKPD, "Evaluation of false positive rate based on exposure–response analyses for two compounds in fixed-dose combination products"

L K Stamp, M L Barclay, J L O'Donnell, M Zhang, J Drake, C Frampton and P T Chapman (2011) CPT, "Relationship Between Serum Urate and Plasma Oxypurinol in the Management of Gout: Determination of Minimum Plasma Oxypurinol Concentration to …

Smith PB, et al. Pediatr Infect Dis J. 2011 Aug 8. "Population Pharmacokinetics of Meropenem in Plasma and Cerebrospinal Fluid of Infants With Suspected or Complicated Intra-abdominal Infections"

Kazuhisa Tsuruta, Yoshinobu Yamada, Masashi Serada, Yusuke Tanigawara (2011) JCP, "Model-Based Analysis of Covariate Effects on Population Pharmacokinetics of Thrombomodulin Alfa in Patients With Disseminated Intravascular Coagulation and …

K Maeda, J Takano, Y Ikeda, T Fujita, Y Oyama, K Nozawa, Y Kumagai and Y Sugiyama (2011) "Nonlinear Pharmacokinetics of Oral Quinidine and Verapamil in Healthy Subjects: A Clinical Microdosing Study" PDF もダウンロードできます。

Khandelwal A, Harling K, Jonsson EN, Hooker AC, Karlsson MO (2011) AAPS J, "A Fast Method for Testing Covariates in Population PK/PD Models" The proposed method is a first-order conditional estimation (FOCE)-based linear approximation of t…

Seongho Kim and Lang Li (2011) "A novel global search algorithm for nonlinear mixed-effects models using particle swarm optimization"

Hannah M Jones, Phylinda LS Chan, Piet H van der Graaf, Robert Webster (2011), "Use of modelling & simulation techniques to support decision making on the progression of PF-04878691, a TLR7 agonist being developed for Hepatitis C"

Bizzotto R, Zamuner S, Mezzalana E, De Nicolao G, Gomeni R, Hooker AC, Karlsson MO. (2011) "Multinomial Logistic Functions in Markov Chain Models of Sleep Architecture: Internal and External Validation and Covariate Analysis"

Maria C. Kjellsson, Daniele Ouellet, Brian Corrigan and Mats O. Karlsson (2011), "Modeling Sleep Data for a New Drug in Development using Markov Mixed-Effects Models"

Catherine M. T. Sherwin, Lili Ding, Jennifer Kaplan, Michael G. Spigarelli and Alexander A. Vinks (2011) "Optimal study design for pioglitazone in septic pediatric patients" Kayode Ogungbenro and Leon Aarons (2011) "Population Fisher infor…

Ogungbenro K, Aarons L. (2011) J PKPD, "Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments"

Christoffer W. Tornøe, Christine E. Garnett, Yaning Wang, Jeffry Florian, Michael Li, Jogarao V. Gobburu (2011) "Creation of a Knowledge Management System for QT Analyses"

Piet H. van der Graaf and Neil Benson (2011), "Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development" this is the quantitative analysis of the dynamic interactions bet…

Mahesh N. Samtani, et al (2011) JCP, "An Improved Model for Disease Progression in Patients From the Alzheimer’s Disease Neuroimaging Initiative"

Xu Steven Xu, Adrian Dunne, Holly Kimko, Partha Nandy and An Vermeulen (2011) J PKPD, "Impact of low percentage of data below the quantification limit on parameter estimates of pharmacokinetic models" Therefore, it is important to balance …

Jae Eun Ahn, Elodie L. Plan, Mats O. Karlsson, Raymond Miller (2011) "Modeling Longitudinal Daily Seizure Frequency Data From Pregabalin Add-On Treatment"

Bertrand J, Laffont CM, Mentré F, Chenel M, Comets E. (2011) AAPS J., "Development of a Complex Parent-Metabolite Joint Population Pharmacokinetic Model"

Mao Hagihara, Hidefumi Kasai, Takumi Umemura, Takahiro Kato, Takaaki Hasegawa and Hiroshige Mikamo (2011), JOURNAL OF INFECTION AND CHEMOTHERAPY, "Pharmacokinetic-pharmacodynamic study of itraconazole in patients with fungal infections in …

D R Abernethy, J Woodcock and L J Lesko (2011) CPT, "Pharmacological Mechanism-Based Drug Safety Assessment and Prediction"

Sun X, Li J. (2011) BMC Med Inform Decis Mak, "PKreport: report generation for checking population pharmacokinetic model assumptions"

Piet H. van der Graaf and Neil Benson (2011), "http://www.springerlink.com/content/nm88844m0531x6t0/:ttile=Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development"

Sun X, Wu K, Cook D. (2011), Comput Methods Programs Biomed, "PKgraph: An R package for graphically diagnosing population pharmacokinetic models"

Kei Akimoto, Ute Klinkhardt, Andreas Zeiher, Margit Niethammer, Sebastian Harder (2011), "Anticoagulation With Argatroban for Elective Percutaneous Coronary Intervention, Population Pharmacokinetics and Pharmacokinetic-Pharmacodynamic Rela…

A. Matsui, J. Azuma, J. W. Witcher, A. J. Long, J.-M. Sauer, B. P. Smith, K. A. DeSante, H. A. Read, M. Takahashi, M. Nakano (2011) JCP, "Pharmacokinetics, Safety, and Tolerability of Atomoxetine and Effect of CYP2D6*10/*10 Genotype in Hea…

Tanii H, Shitara Y, Horie T (2011) Eur J Clin Pharmacol, "Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women" 谷井さん

Celine Marielle Laffont and Didier Concordet (2011) Pharm Res, "A New Exact Test for the Evaluation of Population Pharmacokinetic and/or Pharmacodynamic Models Using Random Projections" Within-subject dependency of observations has a stron…