Visual predictive check (VPC)

• Post, Freijer, Ploeger and Meindert Danhof (Online First) J PKPD, "Extensions to the Visual Predictive Check to facilitate model performance evaluation"

in this investigation the VPC is extended with two methods to support a less subjective and thereby more adequate evaluation of model performance: (i) the Quantified Visual Predictive Check (QVPC) and (ii) the Bootstrap Visual Predictive Check (BVPC). (...) The proposed extensions to the VPC are illustrated by a pharmacokinetic simulation example and applied to a pharmacodynamic disease progression example.

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