EJCP

EJCP 61(5,6), July 2005

• Antignac, et al., "Population pharmacokinetics of tacrolimus in full liver transplant patients: modelling of the post-operative clearance"

The apparent clearance was approximately zero in the immediate post-operative days (PODs and then rapidly increased as a function of POD to reach a plateau.

• • 1200 回ブートストラップを行って，1074 回成功（成功率 89.5%）．その 1074 回分で集計した．
    • 1000 回成功するように「調整」したな(^^;)．