J PKPD
- Xu Steven Xu, Adrian Dunne, Holly Kimko, Partha Nandy and An Vermeulen (2011) J PKPD, "Impact of low percentage of data below the quantification limit on parameter estimates of pharmacokinetic models"
Therefore, it is important to balance the trade-off between model complexity and relative gain in model improvement when the incidence of BQL data is low.
まあ、そりゃそうだ。