J PKPD

• Wang, Eskridge and Zhang (2008), "Semiparametric mixed-effects analysis of PK/PD models using differential equations"
  • USD32
  • R の nlmeODE を利用したサンプルコード付き
• Ogungbenro and Aarons (2008), "Optimisation of sampling windows design for population pharmacokinetic experiments"
• Rossenu, Gaynor, Vermeulen, Cleton and Dunne (2008), "A nonlinear mixed effects IVIVC model for multi-release drug delivery systems"

Four formulations of Galantamine were used to test this modelling technique