今日の論文

• Bhattaram, ..., and Gobburu (2005) AAPS J, "Impact of Pharmacometrics on Drug Approval and Labeling Decisions: A Survey of 42 New Drug Applications"
• Mandema, et al (2005) AAPS J, "Model-Based Development of Gemcabene, a New Lipid-Altering Agent"
• Jadhav & Gobburu (2005) AAPS J, "A New Equivalence Based Metric for Predictive Check to Qualify Mixed-Effects Models"
• de Lange, et al (2005) AAPS J, "Toward the Prediction of CNS Drug-Effect Profiles in Physiological and Pathological Conditions Using Microdialysis and Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling"
• Chien, ..., de Alwis, and Sinha (2005) AAPS J, "Pharmacokinetics/Pharmacodynamics and the Stages of Drug Development: Role of Modeling and Simulation"
• Piotrovsky (2005) AAPS J, "Pharmacokinetic-Pharmacodynamic Modeling in the Data Analysis and Interpretation of Drug-induced QT/QTc Prolongation"
• Hooker & Vicini (2005) AAPS J, "Simultaneous Population Optimal Design for Pharmacokinetic-Pharmacodynamic Experiments"
• Bhattycharyya, et al (2005) AAPS J, "Equivalence Studies for Complex Active Ingredients and Dosage Forms"